P53 (15W6) Rabbit Monoclonal Antibody

Product Specifications

Background

Plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor.

Product Name Alternative

Cellular tumor antigen p53; Phosphoprotein p53; TP53; Tumor suppressor p53

Swiss Prot

P04637

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC, IP

Field of Research

Cell Biology

Purification

Affinity purification

Dilution

WB 1:1000-1:5000, IHC 1:50-1:100, ICC/IF 1:100-1:200, FC 1:200-1:2000, IP 1:20-1:50

Form

Liquid

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.