STAT5a (1Y19) Rabbit Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL- induced transcription. Regulates the expression of milk proteins during lactation.

Product Name Alternative

MGF; MPF; Mammary gland factor; STA5A; STAT5; STAT5A

Gene Name

STAT5A

Gene ID

6776

Swiss Prot

P42229

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC, IP

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:200-1:1000, ICC/IF 1:100-1:500, FC 1:50-1:200, IP 1:20-1:50

Form

Liquid

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.