Alpha Fodrin (15V11) Rabbit Monoclonal Antibody

Fodrin (also named nonerythroid spectrin) is a universally expressed membrane-associated cytoskeletal protein consisting of alpha- and beta-subunits (1) . This protein is important for maintaining normal membrane structure and supporting cell surface protein function (1) . Alpha-fodrin is one of the primary targets cleaved by caspases during apoptosis. Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.