LDL Receptor (14L10) Rabbit Monoclonal Antibody
Product Specifications
Background
Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
Product Name Alternative
FH ; FHC ; LDL receptor; LDLCQ2; LDLR ; Low Density Lipoprotein Receptor; Low density lipoprotein receptor class A domain containing protein 3
Gene Name
LDLR
Gene ID
3949
Swiss Prot
P01130
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, FC
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:20-1:100, FC 1:20-1:50
Form
Liquid
Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Modification
Unmodified
Molecular Weight
95kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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