SHC Rabbit Monoclonal Antibody
Product Specifications
Background
Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals.
Product Name Alternative
SHC1; SHC; SHCA; SHC-transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1
Gene Name
SHC1
Gene ID
6464
Swiss Prot
P29353
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC
Field of Research
Neuroscience
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Form
Liquid
Buffer
Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Modification
Unmodified
Molecular Weight
Calculated MW:63 kDa; Observed MW: 46,52,66 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6310330-01 0.1 mL
ILK, Phosphorylated (S343) (ILK, ILK1, ILK2, Integrin-linked protein kinase, 59kD serine/threonine-protein kinase, ILK-1, ILK-2, p59ILK) (MaxLight 650)
Ask
View Details 
MBS6310330-02 5x 0.1 mL
ILK, Phosphorylated (S343) (ILK, ILK1, ILK2, Integrin-linked protein kinase, 59kD serine/threonine-protein kinase, ILK-1, ILK-2, p59ILK) (MaxLight 650)
Ask
View Details GTR15327958 1 Vial
Lentiviral human USP17L7 shRNA (UAS) - Lentiviral human USP17L7 shRNA (UAS) plasmid
Ask
View Details