PCBP2 Rabbit Monoclonal Antibody
Product Specifications
Background
Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly (rC) -binding protein. Binds also poly (rU) . Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509) . It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:19881509) .
Product Name Alternative
HNRPE2; HNRNPE2; hnRNP-E2
Gene Name
PCBP2
Gene ID
5094
Swiss Prot
Q15366
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IP
Field of Research
Microbiology
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IP 1:20-1:50
Form
Liquid
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Modification
Unmodified
Molecular Weight
Calculated MW: 39 kDa; Observed MW: 35-45 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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