P73 Rabbit Monoclonal Antibody
Product Specifications
Background
P73 IS a protein of the p53 family of proteins. Participates in the apoptotic response to DNA damage. Phosphorylated in a cell cycle-dependent manner and negatively regulated by CDKs. When overproduced, activates transcription from p53-responsive promoters and induces apoptosis. May be a tumor suppressor protein. Seven alternatively-spliced isoforms have been described.
Product Name Alternative
TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein
Gene Name
TP73
Gene ID
7161
Swiss Prot
O15350
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, FC
Field of Research
Cell Biology
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200, FC 1:50-1:100
Form
Liquid
Buffer
Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Modification
Unmodified
Molecular Weight
Calculated MW:70 kDa; Observed MW: 70,60 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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