MLKL Rabbit Monoclonal Antibody
Product Specifications
Background
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Product Name Alternative
MLKL
Gene Name
MLKL
Gene ID
197259
Swiss Prot
Q8NB16
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC
Field of Research
Signal Transduction
Purification
Affinity Chromatography
Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Form
Liquid
Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 54 kDa; Observed MW: 54 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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