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MLH1 Rabbit Monoclonal Antibody

Product Specifications

Background

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.

Product Name Alternative

MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1

Gene Name

MLH1

Gene ID

4292

Swiss Prot

P40692

Host

Rabbit

Reactivity

Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity Purification

Dilution

WB 1:500-1:1000

Form

Liquid

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Modification

Unmodified

Molecular Weight

Calculated MW: 85 kDa; Observed MW: 85 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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