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MAPK6 Rabbit Monoclonal Antibody

Product Specifications

Background

Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle .

Product Name Alternative

ERK3; PRKM6; p97MAPK; HsT17250; ERK-3

Gene Name

MAPK6

Gene ID

5597

Swiss Prot

Q16659

Host

Rabbit

Reactivity

Human, Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, IP

Field of Research

Signal Transduction

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, IHC 1:50-1:100, IP 1:20-1:50

Form

Liquid

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Modification

Unmodified

Molecular Weight

Calculated MW: 83 kDa; Observed MW: 105 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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