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IL-12A Rabbit Monoclonal Antibody

Product Specifications

Background

Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine .IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity .

Product Name Alternative

IL12A; Interleukin-12 subunit alpha, IL-12 subunit p35, IL-12A, Cytotoxic Lymphocyte Maturation Factor 35 kDa; NK cell stimulatory factor chain 1 ; NKSF1

Gene Name

IL12A

Gene ID

3592

Swiss Prot

P29459

Host

Rabbit

Reactivity

Human, Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, FC

Field of Research

Immunology

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, IHC 1:50-1:100, FC 1:50-1:100

Form

Liquid

Buffer

Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Modification

Unmodified

Molecular Weight

Calculated MW:25 kDa; Observed MW: 35 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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