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HtrA2 Rabbit Monoclonal Antibody

Product Specifications

Background

High temperature requirement protein A2 (HtrA2) /Omi is a serine protease with homology to the E. coli HtrA protein (DegP) and is thought to be involved in apoptosis and stress-induced degradation of misfolded proteins. While HtrA2 was orignally identified to be present in either the nucleus or endoplasmic reticulum, subsequent studies have shown that it localizes in mitochondria and is released during apoptosis.

Product Name Alternative

High temperature requirement protein A2; HTRA 2; HtrA like serine protease; HtrA serine peptidase 2; HtrA; E. coli; homolog of; 2; HtrA2; HTRA2_HUMAN; mitochondrial; Omi stress regulated endoprotease; Omi stress-regulated endoprotease; PARK 13; PARK13; Protease serine 25; PRSS 25; PRSS25; Serine protease 25; Serine protease HTRA2; Serine protease HTRA2 mitochondrial; Serine protease htra2 mitochondrial precursor; Serine protease omi; Serine proteinase OMI.

Gene Name

HTRA2

Gene ID

27429

Swiss Prot

O43464

Host

Rabbit

Reactivity

Human, Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, IP

Field of Research

Neuroscience

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200, IP 1:20-1:50

Form

Liquid

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Modification

Unmodified

Molecular Weight

Calculated MW: 49 kDa; Observed MW: 36 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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