CAPON Rabbit Monoclonal Antibody
Product Specifications
Background
Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4 (By similarity) . In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation (PubMed:33523862) .
Product Name Alternative
CAPON, KIAA0464, NOS1AP, Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein, C-terminal PDZ ligand of neuronal nitric oxide synthase protein
Gene Name
NOS1AP
Gene ID
9722
Swiss Prot
O75052
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC/IF, FC
Field of Research
Neuroscience
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, ICC/IF 1:50-1:200, FC 1:50-1:100
Form
Liquid
Buffer
Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Modification
Unmodified
Molecular Weight
Calculated MW:56 kDa; Observed MW: 56 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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