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BRAT1 Rabbit Monoclonal Antibody

Product Specifications

Background

Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress (PubMed:16452482, PubMed:22977523) . Plays a role in regulating mitochondrial function and cell proliferation (PubMed:25070371) . Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors (PubMed:25657994) .

Product Name Alternative

BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1

Gene Name

BRAT1

Gene ID

221927

Swiss Prot

Q6PJG6

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IP

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, IP 1:20-1:50

Form

Liquid

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Modification

Unmodified

Molecular Weight

Calculated MW: 88 kDa; Observed MW: 88 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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