Ataxin 1 Rabbit Monoclonal Antibody

Product Specifications

Background

Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism (PubMed:21475249) . In concert with CIC and ATXN1L, involved in brain development .

Product Name Alternative

ATX1; SCA1; D6S504E

Gene Name

ATXN1

Gene ID

6310

Swiss Prot

P54253

Host

Rabbit

Reactivity

Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IP

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, IP 1:20-1:50

Form

Liquid

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Modification

Unmodified

Molecular Weight

Calculated MW: 87 kDa; Observed MW: 105 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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