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Phospho-Smad3 (Ser423/425) Rabbit Monoclonal Antibody

Product Specifications

Background

Smad3 transcription factor phosphorylated and activated by TGF-beta-type receptors. A receptor-regulated Smad (R-smad) . Binds directly to consensus DNA-binding elements in the promoters of target genes. In mouse required for establishemnt of the mucosal immune response and proper development of skeleton.

Product Name Alternative

SMAD3; MADH3; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3

Gene Name

SMAD3

Gene ID

4088

Swiss Prot

P84022

Host

Rabbit

Reactivity

Human, Rat, Hamster

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Signal Transduction

Purification

Affinity Purification

Dilution

WB 1:500-1:1000

Form

Liquid

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Modification

Phosphorylated

Molecular Weight

Calculated MW: 48 kDa; Observed MW: 52 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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