Wnt5a Rabbit Monoclonal Antibody
Product Specifications
Background
Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression.
Product Name Alternative
WNT5A; Protein Wnt-5a
Gene Name
WNT5A
Gene ID
7474
Swiss Prot
P41221
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC/IF
Field of Research
Neuroscience
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, ICC/IF 1:50-1:200
Form
Liquid
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Modification
Unmodified
Molecular Weight
Calculated MW: 42 kDa; Observed MW: 45 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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