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Ubiquitin Protein Ligase E3A Rabbit Monoclonal Antibody

Product Specifications

Background

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B.

Product Name Alternative

Ubiquitin-protein ligase E3A; UBE3A; E6AP; EPVE6AP; HPVE6A

Gene Name

UBE3A

Gene ID

7337

Swiss Prot

Q05086

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF, IP

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, ICC/IF 1:50-1:200, IP 1:20-1:50

Form

Liquid

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Modification

Unmodified

Molecular Weight

Calculated MW: 101 kDa; Observed MW: 101 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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