Rad21 Rabbit Monoclonal Antibody
Product Specifications
Background
Rad21 is one of the major cohesin subunits that holds sister chromatids together until anaphase, when proteolytic cleavage by separase, a caspaselike enzyme, allows chromosomal separation. Rad21 interacts with Rec8 to form a cohesin complex that functions in sister chromatid alignment. Rad21 is also involved in the repair of double-strand breaks in DNA and is essential for mitotic growth. Rad21 undergoes a C-terminal cleavage induced by diverse stimuli right before apoptosis.
Product Name Alternative
RAD21; HR21; KIAA0078; NXP1; Double-strand-break repair protein rad21 homolog; hHR21; Nuclear matrix protein 1; NXP-1; SCC1 homolog
Gene Name
RAD21
Gene ID
5885
Swiss Prot
O60216
Host
Rabbit
Reactivity
Human, Hamster
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF
Field of Research
Cell Biology
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200
Form
Liquid
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Modification
Unmodified
Molecular Weight
Calculated MW: 72 kDa; Observed MW: 130 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6240469-01 0.1 mL
SCYE1 (Small Inducible Cytokine Subfamily E, Member 1 (Endothelial monocyte-Activating), AIMP1, EMAP2, EMAPII, p43) (MaxLight 750)
Ask
View Details MBS6240469-02 5x 0.1 mL
SCYE1 (Small Inducible Cytokine Subfamily E, Member 1 (Endothelial monocyte-Activating), AIMP1, EMAP2, EMAPII, p43) (MaxLight 750)
Ask
View Details 
