Presenilin 1 Rabbit Monoclonal Antibody

Product Specifications

Background

Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein) . Requires the other members of the gamma-secretase complex to have a protease activity.

Product Name Alternative

PSEN1; AD3; PS1; PSNL1; Presenilin-1; PS-1; Protein S182

Gene Name

PSEN1

Gene ID

5663

Swiss Prot

P49768

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF, IP

Field of Research

Neuroscience

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, ICC/IF 1:50-1:200, IP 1:20-1:50

Form

Liquid

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Modification

Unmodified

Molecular Weight

Calculated MW: 53 kDa; Observed MW: 20 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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