NOXA Rabbit Monoclonal Antibody
Product Specifications
Background
Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.
Product Name Alternative
APR; ATL-derived; NOXA; Pmaip1; Protein Noxa
Gene Name
PMAIP1
Gene ID
5366
Swiss Prot
Q13794
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology
Purification
Affinity Purification
Dilution
WB 1:500-1:1000
Form
Liquid
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Modification
Unmodified
Molecular Weight
Calculated MW: 6 kDa; Observed MW: 10 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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