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ERCC1 Rabbit Monoclonal Antibody

Product Specifications

Background

DNA repair systems operate in all living cells to manage a variety of DNA lesions. Nucleotide excision repair (NER) is implemented in cases where bulky helix-distorting lesions occur, such as those brought about by UV and certain chemicals. Research studies have shown that expression of ERCC1 is related to survival rate and response to chemotherapeutic drugs in several human cancers including non-small cell lung cancer (NSCLC) .

Product Name Alternative

ERCC1; DNA excision repair protein ERCC-1

Gene Name

ERCC1

Gene ID

2067

Swiss Prot

P07992

Host

Rabbit

Reactivity

Human, Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, ICC/IF 1:50-1:200

Form

Liquid

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Modification

Unmodified

Molecular Weight

Calculated MW: 33 kDa; Observed MW: 39 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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