Caspase 1 Rabbit Monoclonal Antibody
Product Specifications
Background
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Can also promote apoptosis.
Product Name Alternative
CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45
Gene Name
CASP1
Gene ID
834
Swiss Prot
P29466
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IP
Field of Research
Cell Biology
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IP 1:20-1:50
Form
Liquid
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Modification
Unmodified
Molecular Weight
Calculated MW: 45 kDa; Observed MW: 45,20 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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