Axin 2 Rabbit Monoclonal Antibody
Product Specifications
Background
Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin .Down-regulates beta-catenin.
Product Name Alternative
Axil; Axin like protein; Axin2; Axis inhibition protein 2; Conductin
Gene Name
AXIN2
Gene ID
8313
Swiss Prot
Q9Y2T1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology
Purification
Affinity Purification
Dilution
WB 1:500-1:1000
Form
Liquid
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Modification
Unmodified
Molecular Weight
Calculated MW: 94 kDa; Observed MW: 94 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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