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Integrin alpha V Rabbit Monoclonal antibody

Product Specifications

Background

The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Product Name Alternative

ITGAV; MSK8; VNRA; Integrin alpha-V; Vitronectin receptor subunit alpha; CD antigen CD51

Gene Name

ITGAV

Gene ID

3685

Swiss Prot

P06756

Host

Rabbit

Reactivity

Human, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF, IP

Field of Research

Cardiovascular

Purification

Affinity Purified

Dilution

WB 1:500-1:1000, ICC/IF 1:50-1:200, IP 1:20-1:50

Form

Liquid

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Modification

Unmodified

Molecular Weight

Calculated MW: 116 kDa; Observed MW: 130 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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