Integrin alpha 5 Rabbit Monoclonal antibody
Product Specifications
Background
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.
Product Name Alternative
ITGA5; FNRA; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD49e
Gene Name
ITGA5
Gene ID
3678
Swiss Prot
P08648
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, IP
Field of Research
Signal Transduction
Purification
Affinity Purified
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, IP 1:20-1:50
Form
Liquid
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Modification
Unmodified
Molecular Weight
Calculated MW: 115 kDa; Observed MW: 150 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Product Datasheet
https://assets.enkilife.com/files/antibody/AMRe04142_Enkilife_EN.pdf
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6360898-01 0.1 mL
UBLCP1, CT (UBLCP1, Ubiquitin-like domain-containing CTD phosphatase 1, Nuclear proteasome inhibitor UBLCP1) (MaxLight 405)
Ask
View Details MBS6360898-02 5x 0.1 mL
UBLCP1, CT (UBLCP1, Ubiquitin-like domain-containing CTD phosphatase 1, Nuclear proteasome inhibitor UBLCP1) (MaxLight 405)
Ask
View Details 
RC210752L1 10 µg
Tartrate Resistant Acid Phosphatase (ACP5) (NM_001611) Human Tagged Lenti ORF Clone
Ask
View Details