EIF4E Rabbit Monoclonal antibody
Product Specifications
Background
EIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.
Product Name Alternative
EIF4E; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein
Gene Name
EIF4E
Gene ID
1977
Swiss Prot
P06730
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, IP
Field of Research
Epigenetics and Nuclear Signaling
Purification
Affinity Purified
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, IP 1:20-1:50
Form
Liquid
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Modification
Unmodified
Molecular Weight
Calculated MW: 25 kDa; Observed MW: 25 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6376036-01 0.1 mL
DEPDC7 (DEP Domain-containing Protein 7, Protein TR2/D15, dJ85M6.4) (MaxLight 550)
Sign In for Pricing
View Details MBS6376036-02 5x 0.1 mL
DEPDC7 (DEP Domain-containing Protein 7, Protein TR2/D15, dJ85M6.4) (MaxLight 550)
Sign In for Pricing
View Details ![2-Chloro-1-[6- (pyrrolidine-1-sulfonyl) -1,2,3,4-tetrahydroquinolin-1-yl]ethan-1-one](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
ZMB22653-01 250 mg
2-Chloro-1-[6- (pyrrolidine-1-sulfonyl) -1,2,3,4-tetrahydroquinolin-1-yl]ethan-1-one
Sign In for Pricing
View Details ZMB22653-02 2.5 g
2-Chloro-1-[6- (pyrrolidine-1-sulfonyl) -1,2,3,4-tetrahydroquinolin-1-yl]ethan-1-one
Sign In for Pricing
View Details 
034845-ML650 100 µL
DUOX2, ID (DUOX2, LNOX2, THOX2, Dual oxidase 2, Large NOX 2, Long NOX 2, NADH/NADPH thyroid oxidase p138-tox, NADPH oxidase/peroxidase DUOX2, NADPH thyroid oxidase 2, Thyroid oxidase 2, p138 thyroid oxidase) (MaxLight 650) discontinued
Sign In for Pricing
View Details