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Phospho-Nrf2 (Ser40) Rabbit Monoclonal antibody

Product Specifications

Background

Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

Product Name Alternative

NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor; erythroid derived 2; like 2

Gene Name

NFE2L2

Gene ID

4780

Swiss Prot

Q16236

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity Purified

Dilution

WB 1:500-1:1000, IHC 1:50-1:100

Form

Liquid

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Modification

Phosphorylated

Molecular Weight

Calculated MW: 68 kDa; Observed MW: 100 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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