USP10 Rabbit Monoclonal antibody

Product Specifications

Background

Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53.

Product Name Alternative

Deubiquitinating enzyme 10; UBPO; USP10

Gene Name

USP10

Gene ID

9100

Swiss Prot

Q14694

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, IP

Field of Research

Cell Biology

Purification

Affinity Purified

Dilution

WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200, IP 1:20-1:50

Form

Liquid

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Modification

Unmodified

Molecular Weight

Calculated MW: 87 kDa; Observed MW: 110 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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