Paxillin Rabbit Monoclonal antibody
Product Specifications
Background
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) . PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions.
Product Name Alternative
PXN; Paxillin
Gene Name
PXN
Gene ID
5829
Swiss Prot
P49023
Host
Rabbit
Reactivity
Human, Rat, Hamster
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, IP
Field of Research
Signal Transduction
Purification
Affinity Purified
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, IP 1:20-1:50
Form
Liquid
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Modification
Unmodified
Molecular Weight
Calculated MW: 65 kDa; Observed MW: 65 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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