Recombinant Human BMP-4

Product Specifications

Background

Bone morphogenic protein-4 (BMP-4) is one of nine structurally related BMPs belonging to the transforming growth factor-beta (TGF-beta) superfamily of secreted proteins. Mature BMP-4 is a dimer that binds to a multimeric transmembrane receptor with serine/threonine kinase activity. BMP-4 has important roles as a signalling molecule in embryonic tissues, including the developing central and peripheral nervous system, musculature and skeleton. BMP-4 as well as its receptors and their signal transduction pathways play a crucial role in the control of the differentiation and proliferation of the different cell types that constitute the anterior pituitary.

Product Name Alternative

Bone morphogenetic protein 4; BMP-4; BMP4; BMP2B; DVR4

Accession Number

P12644

Host

E.coli

Endotoxin

<0.01 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Liquid

Reconstitution

Molecular Weight

13.3 KDa

Shipping Conditions

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.