Recombinant Mouse IL-17RD (C-Fc)

Product Specifications

Background

The Il17rd gene encodes a transmembrane protein of the IL-17 receptor family. IL-17RD, originally termed similar expression to fibroblast growth factor (fgf) genes (Sef) as it belonged to the FGF synexpression group in zebrafish development, is the only orphan receptor without any known ligand within the IL-17R family. IL-17RD is a transmembrane protein shown to inhibit fibroblast growth factor signaling in developmental and cancer contexts, however its role as a tumor suppressor remains to be fully elucidated. The full-length IL-17 RD isoform is expressed in most adult tissues and during embryonic development.

Product Name Alternative

Interleukin-17 receptor D; IL-17 receptor D; IL-17RD; Interleukin-17 receptor-like protein; Il17rd; mSef; Il17rlm; Sef

Accession Number

Q8JZL1

Host

Human Cells

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Lyophilized

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Molecular Weight

58.7 KDa

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Construct

Recombinant Mouse Interleukin-17 receptor D is produced by our Mammalian expression system and the target gene encoding Cys17-Arg299 is expressed with a human IgG1 Fc tag at the C-terminus.