Recombinant Human LILRB1 (C-mFc)

Product Specifications

Background

Leukocyte immunoglobulin-like receptor subfamily B member 1 (LILRB1) is known as CD85j. It is a receptor for class I MHC antigens, the protein can be recognized by a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. It expressed in B cells, monocytes and various dendritic cell (DC) subsets including myeloid, plasmacytoid and tolerogenic DCs. Diseases associated with LILRB1 include Alzheimers Disease 12 and Severe Pre-Eclampsia.

Product Name Alternative

Leukocyte immunoglobulin-like receptor subfamily B member 1; LIR-1; Leukocyte immunoglobulin-like receptor 1; CD85 antigen-like family member J; Immunoglobulin-like transcript 2; ILT-2; Monocyte/macrophage immunoglobulin-like receptor 7; MIR-7; CD85j; LILRB1; ILT2; LIR1; MIR7

Accession Number

ADJ55949.1

Host

Human Cells

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Lyophilized

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Molecular Weight

73.6 KDa

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Construct

Recombinant Leukocyte immunoglobulin-like receptor subfamily B member 1 is produced by our Mammalian expression system and the target gene encoding Gly24-His458 is expressed with a mouse IgG1 Fc tag at the C-terminus.