Recombinant Human TXNDC15 (C-6His)

Thioredoxin domain-containing protein 15 (TXNDC15) is a single-pass type I membrane protein. Mature Human TXNDC15 consists of a 289 amino acid (aa) extracellular region (ECD) with one thioredoxin domain, a 21 aa transmembrane domain, and a 18 aa cytoplasmic region. It has 2 isoforms produced by alternative splicing. Thioredoxins comprise a family of small proteins that, by catalyzing the oxidation of disulfide bonds, participate in redox reactions throughout the cell. Proteins that contain thioredoxin domains do not necessarily convey the oxidative properties of thioredoxins, but generally function as disulfide isomerases that enzymatically rearrange disulfide bonds found in various proteins.

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Recombinant Human Thioredoxin Domain-Containing Protein 15 is produced by our Mammalian expression system and the target gene encoding Val33-Ser321 is expressed with a 6His tag at the C-terminus.