What is the catalog number for Recombinant Human IgG2 Fc (228AA)?

The catalog number for Recombinant Human IgG2 Fc (228AA) is PHH0849.

What sizes are available for Recombinant Human IgG2 Fc (228AA)?

Recombinant Human IgG2 Fc (228AA) is available in the following size(s): 10 µg, 50 µg, 500 µg.

How many pack sizes does Recombinant Human IgG2 Fc (228AA) come in?

Recombinant Human IgG2 Fc (228AA) is available in 3 different pack sizes.

Is Recombinant Human IgG2 Fc (228AA) in stock?

Recombinant Human IgG2 Fc (228AA) is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant Human IgG2 Fc (228AA)

Product Specifications

Background

As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC) . IgG tetramer contains two heavy chains (50 kDa) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment (//

Product Name Alternative

Ig gamma-2 chain C region; IgG2 Fc

Accession Number

P01859

Host

Human Cells

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Lyophilized

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Molecular Weight

25.7 KDa

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Formulation

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 5% Mannitol, 50mM NaCl, 0.05% Tween80, pH6.0.

Construct

Recombinant Human Ig Gamma-2 Chain C Region is produced by our Mammalian expression system and the target gene encoding Glu99-Lys326 (Val161Met, Ser257Ala) is expressed.