Recombinant Mouse Cystatin B (N-6His)

Cystatin B, also called stefin B or liver thiol proteinase inhibitor, is a member of family 1 of the cystatin superfamily. Like Cystatin A, it is an intracellular inhibitor regulating the activities of cysteine proteases of the papain family such as cathepsins B, H and L. Defects in Cystatin-B / CSTB are the cause of progressive myoclonic epilepsy type 1 (EPM1) which is an autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures.

CPI-B; CST6cystatin B (liver thiol proteinase inhibitor) 10STFBcystatin-B; CSTB; cystatin B (stefin B) ; Cystatin B; EPM1; Liver thiol proteinase inhibitor; PME; Stefin B; stefin-B

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Recombinant Mouse Cystatin-B is produced by our E.coli expression system and the target gene encoding Met1-Phe98 is expressed with a 6His tag at the N-terminus.