Recombinant Human CD200 R1 (C-Fc)

Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif) . The receptor-substrate interaction may function as a myeloid downregulatory signal.

Cell Surface Glycoprotein CD200 Receptor 1; CD200 Cell Surface Glycoprotein Receptor; Cell Surface Glycoprotein OX2 Receptor 1; CD200R1; CD200R; CRTR2; MOX2R; OX2R

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Recombinant Human CD200 Receptor 1 is produced by our Mammalian expression system and the target gene encoding Ala27-Leu266 is expressed with a human IgG1 Fc tag at the C-terminus.