Recombinant Human ApoH (C-6His)

Apolipoprotein H (ApoH) is a 50 kDa variably glycosylated member of the complement control superfamily of proteins. Human ApoH is a major phospholipid binding protein and an important component to measure in the assessment of anti-phospholipid syndrome. Hepatocyte-derived ApoH binds to negatively charged phospholipids . It circulates as a component of lipoprotein particles and as a lipid-free serum protein. Human ApoH is also more specific than anti-cardiolipin antibodies and its presence correlates better with thrombotic risk. Mature human ApoH shares 76% and 82% aa sequence identity with mouse and rat ApoH.

Beta-2-Glycoprotein 1; APC inhibitor; Activated Protein C-Binding Protein; Anticardiolipin Cofactor; Apolipoprotein H; Apo-H; Beta-2-Glycoprotein I; B2GPIBeta (2) GPI; APOH; B2G1

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Recombinant Human Apolipoprotein H is produced by our Mammalian expression system and the target gene encoding Gly20-Cys345 is expressed with a 6His tag at the C-terminus.