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Recombinant Human LMIR2 (C-Fc)

Product Specifications

Background

CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells, granulocytes, most myeloid cells, dendritic cells, and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.

Product Name Alternative

CMRF35-Like Molecule 6; CLM-6; CD300 Antigen-Like Family Member C; CMRF35-A1; CMRF-35; Immunoglobulin Superfamily Member 16; IgSF16; CD300c; CD300C; CMRF35; CMRF35A; CMRF35A1; IGSF16

Accession Number

Q08708

Host

Human Cells

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Lyophilized

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Molecular Weight

44.9 KDa

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Product Datasheet

https://assets.enkilife.com/files/Protein/PHH0325_EnkiLife.pdf

Formulation

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH7.4.

Construct

Recombinant Human Leukocyte Mono Ig-like Receptor 2 is produced by our Mammalian expression system and the target gene encoding Gly21-Arg183 is expressed with a human IgG1 Fc tag at the C-terminus.

Species

Human

Available Sizes

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