Recombinant Human IL-2 R beta&IL-2 R alpha&IL-2 R gamma Heterotrimer Protein (C-Fc)

Proliferation of T lymphocytes is triggered by the interaction of IL-2 with its specific receptor following T lymphocyte activation. The receptor for IL-2 consists of at least three distinct subunits, the alpha chain (IL-2Rα), the beta chain (IL-2Rβ), and the gamma chain (IL-2Rγ) . Interleukin-2 (lL-2), one of the first lymphokines to be identified, plays a central role in the clonal expansion of activated T lymphocytes (T cells) by interacting with its specific cell surface receptor (IL-2 receptor) . Antigen-specific, clonal proliferation of T cells is initiated via a process of signal transduction, wherein the specific interaction of the antigen/MHC molecule and T cell antigen receptor complex (TCR) triggers the expression of IL-2 and its homologous receptor (IL-2R) .

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Recombinant HumanIL-2 R beta&IL-2 R alpha&IL-2 R gamma Heterotrimer is produced by our Mammalian expression system and the target gene encoding Met1-Ser212&Leu23-Asn254&Met1-Asp239 is expressed with a human IgG1 Fc tag at the C-terminus.