Recombinant Human DLL3 (353-492, C-6His)
Product Specifications
Background
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 is highly expressed in tumor cells and could be involved in the modification of tumor (immune) microenvironment. Neuroendocrine carcinomas are very aggressive tumors with few treatment options. DLL3 seems to be an optimal target for therapeutic intervention, as it is expressed mainly on the membrane of tumor cells with neuroendocrine origin.
Product Name Alternative
Delta-like protein 3; Drosophila Delta homolog 3; Delta3; DLL3
Accession Number
Q9NYJ7
Host
Human Cells
Endotoxin
<1 EU/µg as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE
Form
Liquid
Molecular Weight
15.4 KDa
Shipping Conditions
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Product Datasheet
https://assets.enkilife.com/files/Protein/PHH2463_EnkiLife.pdf
Formulation
Supplied as a 0.2 μm filtered solution of 20mM PB, 100mM NaCl, 8% Sucrose, 20% Glycerol, 0.05% Tween80, pH6.0.
Construct
Recombinant Human Delta-like protein 3 is produced by our Mammalian expression system and the target gene encoding Arg353-Leu492 is expressed with a 6His tag at C-terminus.
Species
Human
Available Sizes
Curated Selection
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