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Recombinant SARS-CoV-2 3C-like Proteinase (C-6His)

Product Specifications

Background

The viral main proteinase (M pro , also called 3CL pro), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.

Product Name Alternative

3C-like Proteinase; M Proteinase; 3CL Proteinase

Accession Number

P0DTC1

Host

E.coli

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Liquid

Molecular Weight

33.8 kDa

Shipping Conditions

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Formulation

Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 1mM EDTA, pH7.3.

Construct

Recombinant SARS-CoV-2 3C-like Proteinase is produced by our E.coli expression system and the target gene encoding Ser3264-Gln3569 is expressed.

Species

SARS-CoV-2

Available Sizes

Frequently Asked Questions

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