What is the catalog number for Recombinant Rhesus Macaque ACE-2 (C-10His)?

The catalog number for Recombinant Rhesus Macaque ACE-2 (C-10His) is PHV2272.

What sizes are available for Recombinant Rhesus Macaque ACE-2 (C-10His)?

Recombinant Rhesus Macaque ACE-2 (C-10His) is available in the following size(s): 10 µg, 50 µg, 500 µg.

How many pack sizes does Recombinant Rhesus Macaque ACE-2 (C-10His) come in?

Recombinant Rhesus Macaque ACE-2 (C-10His) is available in 3 different pack sizes.

Is Recombinant Rhesus Macaque ACE-2 (C-10His) in stock?

Recombinant Rhesus Macaque ACE-2 (C-10His) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Recombinant Rhesus Macaque ACE-2 (C-10His)?

Recombinant Rhesus Macaque ACE-2 (C-10His) is requires dry ice shipping.

Recombinant Rhesus Macaque ACE-2 (C-10His)

Product Specifications

Background

Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.

Product Name Alternative

Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2

Accession Number

ACI04564.1

Host

Human Cells

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Liquid

Molecular Weight

85.1 KDa

Shipping Conditions

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Formulation

Supplied as a 0.2 μm filtered solution of 25mM Tris-HCl, 150mM NaCl, 1mM ZnCl2, pH 7.5.

Construct

Recombinant Rhesus Macaque Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Val739 is expressed with a 10His tag at the C-terminus.