Recombinant Human Galectin-9 (N-GST)
Product Specifications
Background
Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkins disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1
Product Name Alternative
Galectin-9; Gal-9; Ecalectin; Tumor antigen HOM-HD-21; LGALS9; Gal-9delta5
Accession Number
O00182-2
Host
E.coli
Endotoxin
<1 EU/µg as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE
Form
Liquid
Molecular Weight
62.2 KDa
Shipping Conditions
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Formulation
Supplied as a 0.2 μm filtered solution of 1M PBS, 100 mM GSH, 15% Glycerol, pH 8.0.
Construct
Recombinant Human Galectin-9 is produced by our E.coli expression system and the target gene encoding Met1-Thr323 is expressed with a GST tag at the N-terminus.
Species
Human
Available Sizes
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