What is the catalog number for Recombinant Human UROIIIS (C-6His)?

The catalog number for Recombinant Human UROIIIS (C-6His) is PEH1797.

What sizes are available for Recombinant Human UROIIIS (C-6His)?

Recombinant Human UROIIIS (C-6His) is available in the following size(s): 10 µg, 50 µg, 500 µg.

How many pack sizes does Recombinant Human UROIIIS (C-6His) come in?

Recombinant Human UROIIIS (C-6His) is available in 3 different pack sizes.

Is Recombinant Human UROIIIS (C-6His) in stock?

Recombinant Human UROIIIS (C-6His) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Recombinant Human UROIIIS (C-6His)?

Recombinant Human UROIIIS (C-6His) is requires dry ice shipping.

Recombinant Human UROIIIS (C-6His)

Product Specifications

Background

Uroporphyrinogen-III Synthase is an enzyme which belongs to the uroporphyrinogen-III synthase family. Uroporphyrinogen-III Synthase is ubiquitous and it is involved in Porphyrin metabolism. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as Methionine synthesis (Vitamin B12) or oxygen transport (Heme) . Uroporphyrinogen-III Synthase can catalyze cyclization of the linear Tetrapyrrole, Hydroxymethylbilane, to the Macrocyclic Uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of Porphyrins. Defects in Uroporphyrinogen-III Synthase are the cause of Congenital Erythropoietic Porphyria (CEP) .

Product Name Alternative

Uroporphyrinogen-III Synthase; UROIIIS; UROS; Hydroxymethylbilane Hydrolyase [Cyclizing]; Uroporphyrinogen-III Cosynthase; UROS

Accession Number

P10746

Host

E.coli

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Liquid

Molecular Weight

29.7 KDa

Shipping Conditions

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 10% Glycerol, pH 8.0.

Construct

Recombinant Human Uroporphyrinogen-III Synthase is produced by our E.coli expression system and the target gene encoding Met1-Cys265 is expressed with a 6His tag at the C-terminus.