Recombinant Human TRIM (C-6His)

Product Specifications

Background

T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus, and to a lesser extent in the spleen, lymph node, and peripheral blood lymphocytes. TRAT1 is phosphorylated on tyrosines by LCK or FYN upon TCR activation. Its function is to stabilizes the TCR (T-cell antigen receptor) /CD3 complex at the surface of T-cells.

Product Name Alternative

T-Cell Receptor-Associated Transmembrane Adapter 1; T-Cell Receptor-Interacting Molecule; TRIM; pp29/30; TRAT1; TCRIM; HSPC062

Accession Number

Q6PIZ9

Host

E.coli

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Liquid

Molecular Weight

19.4 KDa

Shipping Conditions

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM EDTA, 20% Glycerol, pH8.0.

Construct

Recombinant Human T Cell Receptor Interacting Molecule is produced by our E.coli expression system and the target gene encoding Asn29-Asn186 is expressed with a 6His tag at the C-terminus.