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Recombinant Mouse TGM2 (C-6His)

Product Specifications

Background

Protein-glutamine gamma-glutamyltransferase 2 (TGM2) is a 78-kDa, calcium dependent enzyme, It belongs to the transglutaminase superfamily and transglutaminase family. The protein encoded by this TGM2 gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. TGM2 is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

Product Name Alternative

Protein-glutamine gamma-glutamyltransferase 2; Tgm2; Tissue transglutaminase; Transglutaminase C; TGase-2

Accession Number

P21981

Host

Human Cells

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Liquid

Molecular Weight

78 KDa

Shipping Conditions

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 7.5.

Construct

Recombinant Mouse Transglutaminase 2 is produced by our Mammalian expression system and the target gene encoding Ala2-Ala686 is expressed with a 6His tag at the C-terminus.

Species

Mouse

Available Sizes

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