Recombinant Human SENP2
Product Specifications
Background
SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.
Product Name Alternative
Sentrin-specific protease 2; Axam2; SMT3-specific isopeptidase 2; Sentrin/SUMO-specific protease SENP2; KIAA1331; SENP2.
Accession Number
Q9HC62
Host
E.coli
Endotoxin
<1 EU/µg as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE
Form
Liquid
Molecular Weight
26.8 KDa
Shipping Conditions
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Formulation
Supplied as a 0.2 μm filtered solution of 50mM HEPES, 5% Glycerol, pH 7.4.
Construct
Recombinant Human Sentrin-specific Protease 2 is produced by our E.coli expression system and the target gene encoding Asp363-Leu589 is expressed.
Species
Human
Available Sizes
Frequently Asked Questions
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