Recombinant Mouse S100A15A

Product Specifications

Background

Members of the S100 protein family are involved in calcium- or zinc-dependent cellular functions and regulate immune-mechanisms, cell proliferation and differentiation. Some S100 members have been established as tumor markers because they are dysregulated during carcinogenesis. Psoriasin (S100A7) and koebnerisin (S100A15) are highly homologous proteins that have been first described in psoriasis, which is characterized by disturbed epidermal maturation and chronic inflammation. Several studies showed that the coexpression of the hS100A7 and hS100A15 in psoriasis suggests that both proteins participate in keratinocyte maturation, proliferation and/or skin inflammation.

Product Name Alternative

S100 calcium-binding protein A15A; Protein S100-A15A; Protein S100-A7A; S100 calcium-binding protein A7A; S100a15a

Accession Number

Q6S5I3

Host

E.coli

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Liquid

Molecular Weight

12.9 KDa

Shipping Conditions

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 30% Glycerol, 1mM DTT, pH 8.0.

Construct

Recombinant Mouse S100 Calcium Binding Protein A15A is produced by our E.coli expression system and the target gene encoding Met1-Tyr108 is expressed.