What is the catalog number for Recombinant Human Sialidase-1 (C-6His)?

The catalog number for Recombinant Human Sialidase-1 (C-6His) is PHH1207.

What sizes are available for Recombinant Human Sialidase-1 (C-6His)?

Recombinant Human Sialidase-1 (C-6His) is available in the following size(s): 10 µg, 50 µg, 500 µg.

How many pack sizes does Recombinant Human Sialidase-1 (C-6His) come in?

Recombinant Human Sialidase-1 (C-6His) is available in 3 different pack sizes.

Is Recombinant Human Sialidase-1 (C-6His) in stock?

Recombinant Human Sialidase-1 (C-6His) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Recombinant Human Sialidase-1 (C-6His)?

Recombinant Human Sialidase-1 (C-6His) is requires dry ice shipping.

Recombinant Human Sialidase-1 (C-6His)

Product Specifications

Background

Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues; it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Deficiencies in the human enzyme Sialidase-1 leads to sialidosis, a rare lysosomal storage disease. Sialidase-1 has been shown to interact with Cathepsin A (protective protein), β-galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex.

Product Name Alternative

Sialidase-1; Acetylneuraminyl Hydrolase; G9 Sialidase; Lysosomal Sialidase; N-Acetyl-Alpha-Neuraminidase 1; NEU1; NANH

Accession Number

Q99519

Host

Human Cells

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Liquid

Molecular Weight

41.27 KDa

Shipping Conditions

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Formulation

Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 50% Glycerol, pH 7.4.

Construct

Recombinant Human N-acetyl-alpha-Neuraminidase 1 is produced by our Mammalian expression system and the target gene encoding Glu48-Leu415 is expressed with a 6His tag at the C-terminus.